Thursday, July 26, 2012

Stress and Multiple Sclerosis

Stress is an inevitable part of the human experience. Whether the stress be good or bad, the hard truth of the matter is that it will affect those with Multiple Sclerosis in the same way... 

Poorly.

Those with MS will learn that stress is a damning factor in the diagnosis. If one can learn how to deal with stress, not only will quality of life be improved, but brain lesions could be prevented or slowed (Boyles, 2012).

The most important factor of stress management is the ability to focus on what one can control. Let's face it - life throws curve balls constantly. However, we cannot be in control of these curve balls all the time. Sometimes, we strike out. Other times, we may hit a home run. What needs to be focused on is the ability to focus on the stress in which can be controlled - or the ability to hit a home run.

Foley (2012) explains that some of the stresses with MS include:

* diagnostic uncertainties
* unpredictability of MS
* the invisibility of some symptoms (which can cause people with MS to feel misunderstood by others)
* the visibility of some symptoms, particularly newly emerging ones (to which others may react
* before the person has had the time to adjust)
* the need to adjust and readjust to changing abilities
* financial stress and concerns about employment
* the presence - or possibility - of cognitive impairment
* loss of control (coming and going of unpredictable symptoms)
* the need to make decision about disease-modifying treatment and adjusting to the treatment if it is chosen
* other stress-related instances within life 

So, how can we cope with stress? Stachowiak (2007) explains:
Social Support: When a relapse occurs or symptoms worsen, you may need help to get to your doctor's office, fulfill your responsibilities or just make dinner. Cultivate your network of friends and family. Keep close ties with the people you can depend on. Let them know how important they are in your life. When you are feeling good, try to help them. 
 
Relaxation: Relaxation is the best way to combat stress in your body. When you are under stress, your body releases certain stress-related hormones. By relaxing, you can reverse this process. A breathing technique known as the relations response has been proved to reverse the effects of stress in your body. You can also learn mediation, yoga or gentle stretching. Anything that relaxes you is great - a lukewarm bath, candles, music or whatever works for you.

A book I was given by my brother taught me how to meditate. It is imperative to understand that meditation takes practice and patience. Most times, it is difficult for some to grasp and can be quite frustrating. It took me nearly six months just to have the ability to clear my mind. Even now, after three years, I still find myself having difficulties meditating. However, meditation and yoga have helped me in more ways than I thought.



Planning: We don't like to think about times when symptoms worsen, but having a plan in place will make everything go easier. Think about what would change in your life if you were having a relapse. Who would take you to the doctor? Who would watch the kids? What about work? Go through your typical day and consider how you could deal with each complication. Talk to the people you would need to depend on before you need them. Set aside a little 'relapse fund' for takeout, massages, and anything else you might need. Creating a relapse plan for MS can make a big difference when things are difficult.

Regardless of the stress, regardless if it is good or bad, one with MS must always remember that it will - in one way or another - work itself out. Though it is in human nature to stress, those with MS need to remember that stress can damage more than just an emotional or mental state...

References:

Boyles, S. (2012). Stress management may prevent MS brain lesions. Retrieved July 26, 2012, from http://www.medicinenet.com/script/main/art.asp?articlekey=160193

Foley, F. (2012). Taming stress in Multiple Sclerosis. Retrieved July 26, 2012, from www.nationalmssociety.org/download.aspx?id=153

Stachowiak, J. (2007). Stress and Multiple Sclerosis. Retrieved July 26, 2012, from http://ms.about.com/od/livingwellwithms/a/ms_stress.htm

Wednesday, July 11, 2012

Medications used for MS Patients

Below is a list of medications most commonly used to treat MS. Those highlighted in red are the ones I've taken since being diagnosed six and a half years ago. Currently, I am not on any disease modifying treatments due to liver issues caused by the medications. Eventually, I'll begin treatment again.

Brand Name*
Chemical Name
Usage in MS
amantadine
Fatigue
mineral oil+
Constipation
papaverine
Erectile dysfunction
Ampyra
dalfampridine (formerly called fampridine, 4-aminopyridine)
Walking
Antivert (US)
Bonamine (Can)
meclizine
Nausea; vomiting; dizziness
Atarax
hydroxyzine
Paroxysmal itching
Avonex
interferon beta-1a
Disease-modifying agent
Bactrim; Septra
sulfamethoxazole
Urinary tract infections
Betaseron
interferon beta-1b
Disease-modifying agent
Botox
onabotulinumtoxin A
Spasticity in the upper limbs
Botox
onabotulinumtoxin A
Bladder dysfunction
Cialis
tadalafil
Erectile dysfunction
Cipro
ciprofloxacin
Urinary tract infections
Colace
docusate+
Constipation
Copaxone
glatiramer acetate
Disease-modifying agent
Cymbalta
duloxetine hydrochloride
Depression, pain (neuropathic)
Dantrium
dantrolene
Spasticity
DDAVP Nasal Spray
desmopressin
Urinary frequency
DDAVP Tablets
desmopressin
Urinary frequency
Decadron
dexamethasone
Acute exacerbations
Deltasone
prednisone
Acute exacerbations
Detrol (US)
tolterodine
Bladder dysfunction
Dilantin
phenytoin
Pain (dyesthesias)
Ditropan
oxybutynin
Bladder dysfunction
Ditropan XL
oxybutynin (extended release formula)
Bladder dysfunction
Dulcolax
bisacodyl+
Constipation
Effexor
venlafaxine
Depression
Elavil
amitriptyline
Pain (paresthesias)
Enablex
darifenacin
Bladder dysfunction
Enemeez Mini Enema
docusate stool softener laxative+
Constipation
Extavia
interferon beta-1b
Disease-modifying agent
Fleet Enema
sodium phosphate+
Constipation
Flomax
tamsulosin
Bladder dysfunction
Gablofen
baclofen (intrathecal)
Spasticity
Gilenya
fingolimod
Disease-modifying agent
H.P. Acthar Gel
adrenocorticotropic hormone (ACTH)
Acute exacerbations
Hiprex; Mandelamine
methenamine
Urinary tract infections (preventative)
Hytrin
terazosin
Bladder dysfunction
Intrathecal Baclofen (ITB Therapy)
baclofen (intrathecal)
Spasticity
Klonopin (US)
Rivotril (Can)
clonazepam
Tremor; pain; spasticity
Laniazid; Nydrazid
isoniazid
Tremor
Levitra
vardenafil
Erectile dysfunction
Lioresal
baclofen
Spasticity
Macrodantin
nitrofurantoin
Urinary tract infections
Metamucil
psyllium hydrophilic mucilloid+
Constipation
Minipress
prazosin
Bladder dysfunction
MUSE
alprostadil
Erectile dysfunction
Neurontin
gabapentin
Pain (dysesthesias)
Nuedexta
dextromethorphan + quinidine
Pseudobulbar affect
Novantrone
mitoxantrone
Disease-modifying agent
Oxytrol (Oxybutynin Transdermal System)
oxybutynin
Bladder dysfunction
Pamelor (US)
Aventyl (Can)
nortriptyline
Pain (parasthesias)
Paxil
paroxetine
Depression
Phillips' Milk of Magnesia
magnesium hydroxide+
Constipation
Pro-Banthine
propantheline bromide
Bladder dysfunction
Prostin VR
alprostadil
Erectile dysfunction
Provigil
modafinil
Fatigue
Prozac
fluoxetine
Depression; fatigue
Pyridium
phenazopyridine
Urinary tract infections (symptom relief)
Rebif
interferon beta-1a
Disease-modifying agent
Sanctura
trospium chloride
Bladder dysfunction
Sani-Supp suppository (US)
glycerin+
Constipation
Solu-Medrol
methylprednisolone
Acute exacerbations
Tegretol
carbamazepine
Pain (trigeminal neuralgia)
Tofranil
imipramine
Bladder dysfunction; Pain
Tysabri
natalizumab
Disease-modifying agent
Valium
diazepam
Spasticity (muscle spasms)
Vesicare (US)
solifenacin succinate
Bladder dysfunction
Viagra
sildenafil
Erectile dysfunction
Wellbutrin
bupropion
Depression
Zanaflex
tizanidine
Spasticity
Zoloft
sertraline
Depression